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Lesk: Introduction to Genomics

Chapter 03

Please note: the filesize of some of the rotating structures is over 1MB and they may take a moment to view

Page 155, Fig 3.7a

Three-dimensional structure of 16S rRNA from the Escherichia coli ribosome [2AVY], showing the region of Figure 3.6(a) highlighted in red and blue.
rotating [1.68MB]; static

Page 155, Fig 3.7b

Detailed structure of the region shown in Figure 3.6(a). Note that the acute angle between two helical regions drawn in the conventional representation of the secondary structure in the preceding figure is merely a drafting convention and does not correspond to the true three-dimensional structure.
rotating [860KB]; static

Page 161, Fig 3.11

Proteins from thermophiles and hyperthermophiles are enriched in salt bridges relative to their mesophilic homologues. Positively charged sidechains are shown in blue. Negatively charged sidechains are shown in red.

(a) Subunit of glutamate dehydrogenase from mesophilic archaeon Clostridium symbiosum [1HRD].
rotating [1.94MB]; static

(b) Subunit of glutamate dehydrogase from hyperthermophilic archaeon Pyrococcus furiosus [1GTM].
rotating [1.93MB]; static