Bromham: Reading the Story in DNA
Chapter 1
The story in DNA
Or: what kind of information can I get from DNA?
TechBox 1.1 - GenBank
The first chapter of the NCBI handbook (freely available online) explains their databases, including GenBank:
www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=handbook
TechBox 1.2 - DNA sequencing
An explanation of sequencing using an automated sequencing machine, with helpful diagrams, can be found at:
http://allserv.rug.ac.be/~avierstr/principles/seq.html
Case study 1.2 - DNA surveillance: using DNA species identification to trace illegal trade in whale meat
The web-based species identification site that takes a DNA sequence and aligns it against a curated database of reference sequences, and calculates genetic distance to known species is at:
www.dna-surveillance.auckland.ac.nz
Heroes of the genetic revolution 1 - Fred Sanger
You can watch a video of an interview with Frederick Sanger at: www.vega.org.uk/video/programme/18,
or read both of his Nobel lectures at:
http://nobelprize.org/chemistry/laureates/


