« Home

Home » Biosciences » Biochemistry » Taylor & Drickamer: Introduction to Glycobiology: 2e » Student resources » Key Reading References » Chapter 02

Taylor & Drickamer: Introduction to Glycobiology: 2e

Chapter 02

Key References

Imberty, A. (1997) Oligosaccharide structures: theory versus experiment. Current Opinion in Structural Biology 7, 617–623. This paper gives an overview of the methods available for determining oligosaccharide conformation with reference to determination of the conformations of several biologically interesting glycans.
[You must have a username and password to access the full article at http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6VS6-4547DXX-B4-1&_cdi=6254&_user=217827&_orig=browse&_coverDate=10%2F31%2F1997&_sk=999929994&view=c&wchp=dGLzVlz-zSkzk&md5=83d57890c0b128eefd95260892e216fb&ie=/sdarticle.pdf]

Nitz, M., Ling, C.-C., Otter, A., Cutler, J.E., and Bundle, D.R. (2002) The unique solution structure and immunochemistry of the Candida albican b -1,2-mannopyran cell wall antigens. Journal of Biological Chemistry 277, 3440–3446. This paper presents NMR experiments demonstrating that antigenic polysaccharides from yeast form helical structures, providing a good example of the use of the nuclear Overhauser effect in determining glycan conformation.
http://www.jbc.org/cgi/reprint/277/5/3440.pdf

Petrescu, A.J., Butters, T.D., Reinkensmeier, G., Petrescu, S., Platt, F.M., Dwek, R.A., and Wormald, M.R. (1997) The solution NMR structure of glucosylated N-glycans involved in the early stages of glycoprotein biosynthesis and folding. EMBO Journal 16, 4302–4310. This paper provides an example of determination of the conformation of a large, biologically important, oligosaccharide by NMR.
http://www.pubmedcentral.gov/picrender.fcgi?artid=1170056&blobtype=pdf

Petrescu, A.J., Petrescu, S.M., Dwek, R.A., and Wormald, M.R. (1999) A statistical analysis of N- and O-glycan linkage conformations from crystallographic data. Glycobiology 9, 343–352. A comparison of all glycan conformations obtained by crystallography allows general conclusions about preferred conformations of particular linkages to be made.
http://glycob.oxfordjournals.org/cgi/reprint/9/4/343.pdf

Woods, R.J. (1998) Computational carbohydrate chemistry: what theoretical methods can tell us. Glycoconjugate Journal 15, 209–216. The use of molecular dynamic simulations in determining glycan conformation is reviewed.
[You must have a username and password to access the full article at http://www.metapress.com/(1zyjutrce4muaf45rj54t455)/app/home/contribution.asp?referrer=parent&backto=issue,1,13;journal,63,138;searcharticlesresults,1,1;]

Wyss, D.F., Choi, J.S., Li, J., Knoppers, M.H., Willis, K.J., Arulanandam, A.R.N., Smolyar, A., Reinherz, E.L., and Wagner, G. (1995) Conformation and function of the N-linked glycan in the cell adhesion domain of human CD2. Science 269, 1273–1278. This paper presents another example of determination of the conformation of an N-linked oligosaccharide by NMR, in this case with the oligosaccharide still attached to the protein. Not available online.