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Maughan & Gleeson: The Biochemical Basis of Sports Performance

Chapter 05

  1. What is gluconeogenesis and why is this metabolic pathway considered important during prolonged exercise?
  2. What stimulates glycolysis in active skeletal muscle tissue during exercise and how is glucose taken up from the blood?
  3. How can the carbon skeletons of amino acids be used as a fuel for exercise?
  4. What is the normal resting blood glucose concentration in mmoles/litre and why does this not change drastically as a result of increased muscle glucose uptake during exercise?
  5. What stimulates lipolysis in adipose tissue during exercise and how is lipid fuel carried in the blood following its release from adipose tissue?
  6. What is the first stage in the processing of acetyl CoA by the Krebs (TCA) cycle and how many CO2 molecules are produced with every rotation of the Krebs cycle?
  7. What factors influence the blood glucose concentration and how does glucose cross the muscle cell membrane during exercise?
  8. List the possible causes of fatigue during a marathon race.