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Patrick: An Introduction to Medicinal Chemistry 4e

Chapter 16

Further reading

Beck-Sickinger, A., and Weber, P. (2002) Combinatorial strategies in biology and chemistry. John Wiley and Sons, New York.

Bhalay, G., Dunstan, A., and Glen, A. (2000) Supported reagents: opportunities and limitations. Synlett 1846-1859.

Booth, R.J., and Hodges, J.C. (1997) Solid-supported quenching reagents for parallel purification. Journal of the American Chemical Society, 119, 4882-4886 [DOI: 10.1021/ja9634637].

Braeckmans, K., et al. (2002) Encoding microcarriers: present and future technologies. Nature Reviews Drug Discovery, 1, 447-456 [DOI: 10.1038/nrd817] [PubMed: 12119746].

DeWitt, S. H., et al. (1993) ‘Diversomers’: An approach to nonpeptide, nonoligomeric chemical diversity. Proceedings of the National Academy of Sciences of the USA, 90, 6909-6913 [DOI: 10.1073/pnas.90.15.6909] [PubMed: 8394002].

Dittrich, P. S., and Manz, A. (2006) Lab-on-a-chip: microfluidics in drug discovery. Nature Reviews Drug Discovery, 5, 210-218 [DOI: 10.1038/nrd1985] [PubMed: 16518374].

Dobson, C. M. (2004). Chemical space and biology. Nature, 432, 824-828 [DOI: 10.1038/nature03192] [PubMed: 15602547].

Dolle, R. E. (2003) Comprehensive survey of combinatorial library synthesis: 2002. Journal of Combinatorial Chemistry, 5, 693-753 [DOI: 10.1021/cc0340224] [PubMed: 14606800].

Geysen, H. M., et al. (2003) Combinatorial compound libraries for drug discovery: an ongoing challenge. Nature Reviews Drug Discovery, 2, 222-230 [DOI: 10.1038/nrd1035] [PubMed: 12612648].

Guillier, F., Orain, D., and Bradley, M. (2000) Linkers and cleavage strategies in solid-phase organic synthesis and combinatorial chemistry. Chemical Reviews, 100, 2091-2158 [DOI: 10.1021/cr980040+] [PubMed: 11749285].

Houlton, S. (2002) Sweet synthesis. Chemistry in Britain, April, 46-49.

Jung, G. (ed.). (1996) Combinatorial peptide and nonpeptide libraries. VCH, Weinheim.

Kappe, C. O. (2004) Controlled microwave heating in modern organic synthesis. Angewandte Chemie International Edition, 43, 6250-6284 [DOI: 10.1002/anie.200400655].

Le, G. T., et al. (2003) Molecular diversity through sugar scaffolds. Drug Discovery Today, 8, 701-709 [DOI: 10.1016/S1359-6446(03)02751-X].

Ley, S. V., and Baxendale, I. R. (2002) New tools and concepts for modern organic synthesis. Nature Reviews Drug Discovery, 1, 573-586 [DOI: 10.1038/nrd871] [PubMed: 12402498].

Mavandadi, F., and Pilotti, Å. (2006) The impact of microwave-assisted organic synthesis in drug discovery. Drug Discovery Today, 11, 165-174 [DOI: 10.1016/S1359-6446(05)03695-0].

Nicolaou, K. C., et al. (2000) Target-accelerated combinatorial synthesis and discovery of highly potent antibiotics effective against vancomycin-resistant bacteria. Angewandte Chemie, International Edition, 39, 3823-3828 [DOI: 10.1002/(SICI)1521-3773(20000218)39:4<734::AID-ANIE734>3.0.CO;2-I].

Ramstrom, O., and Leh, J.-M. (2002) Drug discovery by dynamic combinatorial libraries. Nature Reviews Drug Discovery, 1, 26-36 [DOI: 10.1038/nrd704].

Reader, J. C. (2004) Automation in medicinal Chemistry. Current Topics in Medicinal Chemistry, 4, 671-686 [DOI: 10.2174/1568026043451069] [PubMed: 15032681].

Terret, N. K. (1998) Combinatorial Chemistry. Oxford University Press, Oxford.

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