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Patrick: An Introduction to Medicinal Chemistry 4e

Chapter 09

Further reading

Aldridge, S. (2003) The DNA story. Chemistry in Britain, April, 28-30.

Burke, M. (2003) On delivery. Chemistry in Britain, February, 36-38.

Dorsett, Y., and Tuschl, T. (2004). siRNAs: applications in functional genomics and potential as therapeutics. Nature Reviews Drug Discovery, 3, 318-329 [DOI: 10.1038/nrd1345] [PubMed: 15060527].

Fortune, J. M., and Osheroff, N. (2000) Topoisomerase II as a target for anticancer drugs. Progress in Nucleic Acid Research and mole bio, 64, 221-253 [DOI: 10.1016/S0079-6603(00)64006-0].

Johnson, I. S. (2003) The trials and tribulations of producing the first genetically engineered drug. Nature Reviews Drug Discovery, 2, 747-751 [DOI: 10.1038/nrd1179] [PubMed: 12951581].

Judson, H. F. (1979) The Eighth Day of Creation. Simon and Schuster, New York.

Kelland, L. (2007) The resurgence of platinum-based cancer chemotherapy. Nature Reviews Cancer, 7, 573-584 [DOI: 10.1038/nrc2167].

Langer, R. (2003) Where a pill won’ t reach. Scientific American, April, 32-39.

Lindpaintner, K. (2002) The impact of pharmacogenetics and pharmacogenomics on drug discovery. Nature Reviews Drug Discovery, 1, 463-469 [DOI: 10.1038/nrd823] [PubMed: 12119748].

Opalinska, J. B., and Gewirtz, A. M. (2002) Nucleic acid therapeutics: basic principles and recent applications. Nature Reviews Drug Discovery, 1, 503-514 [DOI: 10.1038/nrd837] [PubMed: 12120257].

Petricoin, E. F., et al. (2002) Clinical proteomics. Nature Reviews Drug Discovery, 1, 683-695 [DOI: 10.1038/nrd891] [PubMed: 12209149].

Pommier, Y., et al. (1998) Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme. Biochimica et Biophysica Acta, 1400, 83-106 [PubMed: 9748515].

Wang, D., and Lippard, S. J. (2005) Cellular processing of platinum anticancer drugs. Nature Reviews Drug Discovery, 4, 307-320 [DOI: 10.1038/nrd1691] [PubMed: 15789122].

Winter, P. C., Hickey, G. I., and Fletcher, H. L. (1998) Instant Notes Genetics. BIOS Scientific Publishers, Oxford.