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Patrick: An Introduction to Medicinal Chemistry 4e

Chapter 06

Further reading

Aldridge, S. (2003) The DNA story. Chemistry in Britain, April, 28-30.

Breaker, R. R. (2004) Natural and engineered nucleci acids as tools to explore biology. Nature, 432, 838-845 [DOI: 10.1038/nature03195] [PubMed: 15602549].

Burke, M. (2003) On delivery. Chemistry in Britain, February, 36-38.

Dorsett, Y., and Tuschl, T. (2004). siRNAs: applications in functional genomics and potential as therapeutics. Nature Reviews Drug Discovery, 3, 318-329 [DOI: 10.1038/nrd1345] [PubMed: 15060527].

Johnson, I. S. (2003) The trials and tribulations of producing the first genetically engineered drug. Nature Reviews Drug Discovery, 2, 747-751 [DOI: 10.1038/nrd1179] [PubMed: 12951581].

Judson, H. F. (1979) The Eighth Day of Creation. Simon and Schuster, New York.

Langer, R. (2003) Where a pill won’ t reach. Scientific American, April, 32-39.

Lindpaintner, K. (2002) The impact of pharmacogenetics and pharmacogenomics on drug discovery. Nature Reviews Drug Discovery, 1, 463-469 [DOI: 10.1038/nrd823] [PubMed: 12119748].

Nicholl, D. S. T. (2008) An Introduction to Genetic Engineering, 3rd Edition. Cambridge University Press.

Opalinska, J. B., and Gewirtz, A. M. (2002) Nucleic acid therapeutics: basic principles and recent applications. Nature Reviews Drug Discovery, 1, 503-514 [DOI: 10.1038/nrd837] [PubMed: 12120257].

Petricoin, E. F., et al. (2002) Clinical proteomics. Nature Reviews Drug Discovery, 1, 683-695 [DOI: 10.1038/nrd891] [PubMed: 12209149].

Stark, H., et al. (2001). Arrangement of RNA and proteins in the spliceosomal U1 small nuclear ribonucleoprotein particle. Nature, 409, 539-542 [DOI: 10.1038/35054102] [PubMed: 11206553].

Winter, P. C., Hickey, G. I., and Fletcher, H. L. (1998) Instant Notes Genetics. BIOS Scientific Publishers, Oxford.