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Pecorino: Molecular Biology of Cancer 2e

Chapter 08

Further reading

Altucci, L. and Gronemeyer, H. (2001) The promise of retinoids to fight against cancer. Nature Rev. Cancer 1: 181-193. [DOI: 10.1038/35106036]

Dean, M., Fojo, T., and Bates, S. (2005) Tumour stem cells and drug resistance. Nature Rev. Cancer 5: 275-284. [DOI: 10.1038/nrc1590]

Giles, R.H., van Es, J.H., and Clevers, H. (2003) Caught up in a Wnt storm: Wnt signaling in cancer. Biochem. Biophys. Acta 1653: 1-24. [PubMed: 12781368]

Gregorieff, A. and Clevers, H. (2005) Wnt signaling in the intestinal epithelium: from endoderm to cancer. Genes Dev. 19: 877-890. [PubMed: 15833914] [DOI: 10.1101/gad.1295405]

Lee, T., Jenner, R., Boyer, L., Guenther, M., Levine, S., Kumar, R., Chevalier, B., Johnstone, S., Cole, M., and Isono, K. (2006) Control of developmental regulators by polycomb in human embryonic stem cells. Cell 125: 301-313. [PubMed: 16630818] [DOI: 10.1016/j.cell.2006.02.043]

Owens, D.M. and Watt, F.M. (2003) Contribution of stem cells and differentiated cells to epidermal tumors. Nature Rev. Cancer 3: 444-451. [DOI: 10.1038/nrc1096]

Pardal, R., Clarke, M.F., and Morrison, S.J. (2003) Applying the principles of stem-cell biology to cancer. Nature Rev. Cancer 3: 895-902. [DOI: 10.1038/nrc1232]

Perez-Losada, J. and Balmain, A. (2002) Stem-cell hierarchy in skin cancer. Nature Rev. Cancer 3: 434-443. [DOI: 10.1038/nrc1095]

Polakis, P. (2000) Wnt signaling and cancer. Genes Dev. 11: 1837-1851.

Radtke, F. and Clevers, H. (2005) Self-renewal and cancer of the gut: two sides of a coin. Science 307: 1904-1909. [PubMed: 15790842] [DOI: 10.1126/science.1104815]

Reya, T. and Clevers, H. (2005) Wnt signaling in stem cells and cancer. Nature 434: 843-850. [PubMed: 15829953] [DOI: 10.1038/nature03319]

Reya, T., Morrison, S.J., Clarke, M.F., and Weissman, I.L. (2001) Stem cells, cancer, and cancer stem cells. Nature 414: 105-111. [PubMed: 11689955] [DOI: 10.1038/35102167]

Ruiz, I. Altaba, A., Sanchez, P., and Dahmane, N. (2002) Gli and Hedgehog in cancer: tumours, embryos and stem cells. Nature Rev. Cancer 2: 361-372. [DOI: 10.1038/nrc796]

Smalley, M. and Ashworth, A. (2003) Stem cells and breast cancer: a field in transit. Nature Rev. Cancer 3: 832-844. [DOI: 10.1038/nrc1212]

Sparmann, A. and van Lohuizen, M. (2006) Polycomb silencers control cell fate, development and cancer. Nature Rev. Cancer 6: 846-856. [DOI: 10.1038/nrc1991]

Tenen, D.G. (2003) Disruption of differentiation in human cancer: AML shows the way. Nature Rev. Cancer 3: 89-101. [DOI: 10.1038/nrc989]

Vescovi, A.L., Galli, R., and Reynolds, B.A. (2006) Brain tumor stem cells. Nature Rev. Cancer 6: 425-436. [DOI: 10.1038/nrc1889]

Selected Special Topics

Al-Hajj, M., Wicha, M.S., Benito-Hernandez, A., Morrison, S.J., and Clarke, M.F. (2003) Prospective identification of tumorigenic breast cancer cells. Proc. Natl. Acad. Sci. USA 100: 3983-3988. [PubMed: 12629218] [DOI: 10.1073/pnas.0530291100]

Berman, D.M., Karhadkar, S.S., Hallahan, A.R., Pritchard, J.I., Eberhart, C.G., Watkins, D.N., Chen, J.K., Cooper, M.K., Taipale, J., Olson, J.M., and Beachy, P.A. (2002) Medulloblastoma growth inhibition by hedgehog pathway blockade. Science 297: 1559-1561. [PubMed: 12202832] [DOI: 10.1126/science.1073733]

Chenwei, L., Heidt, D.G., Dalerba, P., Burant, C.F., Zhang, L., Adsay, V., Wicha, M., Clarke, M.F., and Simeone, D.M. (2007) Identification of pancreatic cancer stem cells. Cancer Res. 67: 1030-1037. [DOI: 10.1158/0008-5472.CAN-06-2030]

Kwok, C., Zeisig, B.B., and So, C.W. (2006) Forced homo-oligomerization of RARalpha leads to transformation of primary hematopoietic cells. Cancer Cells 9: 73-74. [DOI: 10.1016/j.ccr.2006.01.005]

Lepourcelet, M., Chen, Y.-N.P., France, D.S., Wang, H., Crews, P., Petersen, F., Bruseo, C., Wood, A.W., and Shivdasani, R.A. (2004) Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex. Cancer Cells 5: 91-102. [DOI: 10.1016/S1535-6108(03)00334-9]

Lessard, J. and Sauvageau, G. (2003) Bmi-1 determines the proliferative capacity of normal and leukemic stem cells. Nature 423: 255-260. [PubMed: 12714970] [DOI: 10.1038/nature01572]

O'Brien, C.A., Pollett, A., Gallinger, S., and Dick, J.E. (2006) Identification of a human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445: 106-110. [PubMed: 17122772] [DOI: 10.1038/nature05372]

Reya, T., Duncan, A.W., Ailles, L., Domen, J., Scherer, D.C., Willert, K., Hintz, L., Nusse, R., and Weissman, I.L. (2003) A role for Wnt signaling in self-renewal of haematopoietic stem cells. Nature 423: 409-414. [PubMed: 12717450] [DOI: 10.1038/nature01593]

Ricci-Vitiani, L., Lombardi, D.G., Pilozzi, E., Biffoni, M., Todaro, M., Peschle, C., and De Maria, R. (2006) Identification and expansion of human colon-cancer-initiating cells. Nature 445: 111-115. [PubMed: 17122771] [DOI: 10.1038/nature05384]

Romer, J.T., Kimura, H., Magdaleno, S., Sasai, K., Fuller, C., Baines, H., Connelly, M., Stewart, C.F., Gould, S., Rubin, L.L., and Curran, T. (2004) Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1+/− p53−/− mice. Cancer Cells 6: 229-240. [DOI: 10.1016/j.ccr.2004.08.019]

Salomoni, P. and Pandolfi, P.P. (2002) The role of PML in tumor suppression. Cell 108: 165-170. [PubMed: 11832207] [DOI: 10.1016/S0092-8674(02)00626-8]

Shih, I.-M., Wang, T.-L., Traverso, G., Romans, K., Hamilton, S.R., Ben-Sasson, S., Kinzler, K.W., and Vogelstein, B. (2001) Top-down morphogenesis of colorectal tumors. Proc. Natl. Acad. Sci. USA 98: 2640-2645. [PubMed: 11226292] [DOI: 10.1073/pnas.051629398]

Yilmaz, O.H., Valdez, R., Theisen, B.K., Guo, W., Ferguson, D.O., Wu, H., and Morrison, S.J. (2006) Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 441: 475-482. [PubMed: 16598206] [DOI: 10.1038/nature04703]