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Pecorino: Molecular Biology of Cancer 2e
Chapter 06
Further reading
Bouchet, B.P., de Fromentel, C.C., Puisieux, A., and Galmarini, C.M. (2006) P53 as a target for anti-cancer drug development. Crit. Rev. Oncol. Hematol. 58: 190-207. [PubMed: 16690321] [DOI: 10.1016/j.critrevonc.2005.10.005]
Guimaraes, D.P. and Hainaut, P. (2002) TP53: a key gene in human cancer. Biochimie 84: 83-93. [PubMed: 11900880] [DOI: 10.1016/S0300-9084(01)01356-6]
Lane, D.P. and Lain, S. (2002) Therapeutic exploitation of the p53 pathway. Trends Mol. Med. 8: S38-S42. [PubMed: 11927286] [DOI: 10.1016/S1471-4914(02)02309-2]
Levitt, N.C. and Hickson, I.D. (2002) Caretaker tumour suppressor genes that defend genome integrity. Trends Mol. Med. 8: 179-186. [PubMed: 11927276] [DOI: 10.1016/S1471-4914(02)02298-0]
Macleod, K. (2000) Tumor suppressor genes. Curr. Opin. Genet. Dev. 10: 81-93. [PubMed: 10679386] [DOI: 10.1016/S0959-437X(99)00041-6]
Ostman, A., Hellberg, C., and Bohmer, F.D. (2006) Protein-tyrosine phosphatases and cancer. Nature Rev. Cancer 6: 307-320. [DOI: 10.1038/nrc1837]
Ryan, K.M., Phillips, A.C. and Vousden, K.H. (2001) Regulation and function of the p53 tumour suppressor protein. Curr. Opin. Cell Biol. 13: 332-337. [PubMed: 11343904] [DOI: 10.1016/S0955-0674(00)00216-7]
Scully, R. and Pudget, N. (2002) BRCA1 and BRCA2 in hereditary breast cancer. Biochimie 84: 95-102. [DOI: 10.1016/S0300-9084(01)01359-1]
Sherr, C.J. (2004) Principles of tumor suppression. Cell 116: 235-246. [PubMed: 14744434] [DOI: 10.1016/S0092-8674(03)01075-4]
Sulis, M.L. and Parsons, R. (2003) PTEN: from pathology to biology. Trends Cell Biol. 13: 478-483. [PubMed: 12946627] [DOI: 10.1016/S0962-8924(03)00175-2]
Swanton, C. (2004) Cell-cycle targeted therapies. Lancet Oncol. 5: 27-36. [PubMed: 14700606] [DOI: 10.1016/S1470-2045(03)01321-4]
Volgelstein, B., Lane, D., and Levine, A. (2000) Surfing the p53 network. Nature 408: 307-310. [DOI: 10.1038/35042675]
Selected Special Topics
Bykov, V.J.N., Selivanova, G., and Wiman, K.G. (2003) Small molecules that reactivate mutant p53. Eur. J. Cancer 39: 1828-1834. [PubMed: 12932659] [DOI: 10.1016/S0959-8049(03)00454-4]
Chene, P. (2003) Inhibiting the p53-MDM2 interaction: an important target for cancer therapy. Nature Rev. Cancer 3: 102-109. [DOI: 10.1038/nrc991]
Hemann, M.T., Fridman, J.S., Zilfou, J.T., Hernando, E., Paddison, P.J., Cordon-Cardo, C., Hannon, G.J., and Lowe, S.W. (2003) An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes. Nature Genet. 33: 396-400. [PubMed: 12567186] [DOI: 10.1038/ng1091]
Ries, S. and Korn, W.M. (2002) ONYX-015: mechanisms of action and clinical potential of a replication-selective adenovirus. Br. J. Cancer 86: 5-11. [PubMed: 11857003] [DOI: 10.1038/sj.bjc.6600006]
Sablina, A.A., Budanov, A.V., Ilyinskaya, G.V., Agapova, L.S., Kravchenko, J.E., and Chumakov, P.M. (2005) The antioxidant function of the p53 tumor suppressor. Nature Med. 11: 1306-1313. [PubMed: 16286925] [DOI: 10.1038/nm1320]
Senderowicz, A.M. (2001) Development of cyclin-dependent kinase modulators as novel therapeutic approaches for hematological malignancies. Leukemia 15: 1-9. [PubMed: 11243375] [DOI: 10.1038/sj.leu.2401994]
Slee, E.A. and Lu, X. (2003) The ASPP family: deciding between life and death after DNA damage. Toxicol. Lett. 139: 81-87. [PubMed: 12628742] [DOI: 10.1016/S0378-4274(02)00421-6]
Vassilev, L.T., Vu, B.T., Graves, B., Carvajal, D., Podlaski, F., Filipovic, Z., Kong, N., Kammlott, U., Lukacs, C., Klein, C., Fotouhi, N., and Liu, E.A. (2004) activation of the p53 pathway by small-molecule antagonists of MDM2. Science 303: 844-848. [PubMed: 14704432] [DOI: 10.1126/science.1092472]
Wang, Z., Shen, D., Parsons, D., Bardelli, A., Sager, J., Szabo, S., Ptak, J., Silliman, N., Peters, B., van der Heijden, M., Parmigiani, G., Yan, H., Wang, T.-L., Riggins, G., Powell, S., Willson, J., Markowitz, S., Kinzler, K., Volgelstein, B., and Velculescu, V. (2004) Mutational analysis of the tyrosine phosphatome in colorectal cancers. Science 304: 1164-1166. [DOI: 10.1126/science.1096096]