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Pecorino: Molecular Biology of Cancer 2e

Chapter 03

Further reading

Baylin, S.B. and Herman, J.G. (2000) DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet. 16: 168-174. [PubMed: 10729832] [DOI: 10.1016/S0168-9525(99)01971-X]

Baylin, S.B. and Ohm, J.E. (2006) Epigenetic silencing in cancer-a mechanism for early oncogenic pathway addiction? Nature Rev. Cancer 6: 107-116. [DOI: 10.1038/nrc1799]

Brown, R. and Strathdee, G. (2002) Epigenomics and epigenetic therapy of cancer. Trends Mol. Med. 8(Suppl.): S43-S48. [PubMed: 11927287] [DOI: 10.1016/S1471-4914(02)02314-6]

Esquela-Kerscher, A. and Slack, F.J. (2006) Oncomirs-microRNAs with a role in cancer. Nature Rev. Cancer 6: 259-269. [DOI: 10.1038/nrc1840]

Esteller, M. and Herman, J.G. (2002) Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumors. J. Pathol. 196: 1-7. [PubMed: 11748635] [DOI: 10.1002/path.1024]

Feinberg, A.P. (2007) Phenotypic plasticity and the epigenetics of human disease. Nature 447: 433-440. [PubMed: 17522677] [DOI: 10.1038/nature05919]

Goffin, J. and Eisenhauer, E. (2002) DNA methyltransferase inhibitors-state of the art. Ann. Oncol. 13: 1699-1716. [PubMed: 12419742] [DOI: 10.1093/annonc/mdf314]

Herman, J.G. and Baylin, S.B. (2003) Gene silencing in cancer in association with promoter hypermethylation. N Engl J. Med. 349: 2042-2054. [DOI: 10.1056/NEJMra023075]

Jones, P.A. and Baylin, S.B. (2002) The fundamental role of epigenetic events in cancer. Nature Rev. Genetics 3: 415-428.

Kelland, L.R. (2001) Telomerase: biology and phase 1 trials. Lancet Oncol. 2: 95-102. [PubMed: 11905801] [DOI: 10.1016/S1470-2045(00)00226-6]

Laird, P.W. (2003) The power and the promise of DNA methylation markers. Nature 3: 253-266.

Marks, P.A., Richon, V.M., Breslow, R., and Rifkind, R.A. (2001) Histone deacetylase inhibitors as new cancer drugs. Curr. Opin. Oncol. 13: 477-483. [PubMed: 11673688] [DOI: 10.1097/00001622-200111000-00010]

Milde-Langosch, K. (2005) The Fos family of transcription factors and their role in tumourigenesis. Eur. J. Cancer 41: 2449-2461. [PubMed: 16199154] [DOI: 10.1016/j.ejca.2005.08.008]

Rezler, E.M., Bearss, D.J., and Hurley, L.H. (2002) Telomeres and telomerases as drug targets. Current Opin. Pharmacol. 2: 415-423. [DOI: 10.1016/S1471-4892(02)00182-0]

Schreiber, S.L. and Bernstein, B.E. (2002) Signaling network model of chromatin. Cell 111: 771-778. [PubMed: 12526804] [DOI: 10.1016/S0092-8674(02)01196-0]

Shaulian, E. and Karin, M. (2002) AP-1 as a regulator of cell life and death. Nature Cell Biol. 4: E131-E136. [PubMed: 11988758] [DOI: 10.1038/ncb0502-e131]

Verdun, R.E. and Karlseder, J. (2007) Replication and protection of telomers. Nature 447: 924-931. [PubMed: 17581575] [DOI: 10.1038/nature05976]

White, L.K., Wright, W.E., and Shay, J.W. (2001) Telomerase inhibitors. Trends Biotechnol. 19: 114-120. [PubMed: 11179805] [DOI: 10.1016/S0167-7799(00)01541-9]

Selected Special Topics

Di Croce, L., Raker, V.A., Corsaro, M., Fazi, F., Fanelli, M., Faretta, M., Fuks, F., Lo CoCo, F., Kouzarides, T., Nervi, C., Minucci, S., and Pelicci, P.G. (2002) Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science 295: 1079-1082. [PubMed: 11834837] [DOI: 10.1126/science.1065173]

Gaudet, F., Hodgson, J.G., Eden, A., Jackson-Grusby, L., Dausman, J., Gray, J.W., Leonhardt, H., and Jaenisch, R. (2003) Induction of tumors in mice by genomic hypomethylation. Science 300: 489-492. [PubMed: 12702876] [DOI: 10.1126/science.1083558]

Gayther, S.A., Batley, S.J., Linger, L., Bannister, A., Thorpe, K., Chin, S.-F., Daigo, Y., Russell, P., Wilson, A., Sowter, H.M., Delhanty, J.D.A., Ponder, B.A.J, Kouzarides, T., and Caldas, C. (2000) Mutations truncating the EP300 acetylase in human cancers. Nature Genet. 24: 300-303. [PubMed: 10700188] [DOI: 10.1038/73536]

O'Doherty, A.M., Church, S.W., Russell, S.E.H., Nelson, J., and Hickey, I. (2002) Methylation status of oestrogen receptor-a gene promoter sequence in human ovarian epithelial cell lines. Br. J. Cancer 86: 282-284. [PubMed: 11870520] [DOI: 10.1038/sj.bjc.6600028]

von Zglinicki, T. (2002) Oxidative stress shortens telomeres. Trends Biochem. Sci. 27: 339-344. [DOI: 10.1016/S0968-0004(02)02110-2]

Watson, R.E. and Goodman, J.I. (2002) Effects of phenobarbital on DNA methylation in GC-rich regions of hepatic DNA from mice that exhibit different levels of susceptibility to liver tumorigenesis. Toxicol. Sci. 68: 51-58. [PubMed: 12075110] [DOI: 10.1093/toxsci/68.1.51]

Yanaihara, N., Caplen, N., Bowman, E., Seike, M., Kumamoto, K., Yi, M., Stephens, R.M., Okamoto, A., Yokota, J., Tanaka, T., Calin, G.A., Liu, C.-G., Croce, C.M., and Harris, C.C. (2006) Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cells 9: 189-198. [DOI: 10.1016/j.ccr.2006.01.025]