Immunity: Chapter 08, Specialized Lymphocytes in Early Responses and Homeostasis

One of the two main populations of intraepithelial lymphocytes is composed of CD4 CD8 double-negative and CD8αα T cells. Which of the following contribute(s) to the maintenance and/or activation of these cells?

	a)	IL-7
	b)	classical MHC class I molecules
	c)	bacterial colonization of the bowel
	d)	IL-15
	e)	β7 integrins
CorrectWrong: a, d and e are correct.Your answer has been saved.

Which of the following statements are true?

	a)	The inhibitory receptor PD-1 is induced on IELs by activation.
	b)	NKG2D recognizes stress-induced ligands and augments the signal from the TCR on IEL.
	c)	CD8αα on IEL binds the non-classical MHC class I molecule TL.
	d)	The non-classical MHC class I molecule H2-M3 recognizes formylated peptides characteristic of mitochondrial and bacterial proteins.
	e)	Specialized H2-M3-restricted T cells are cytotoxic.
CorrectWrong: b c d and e are true.Your answer has been saved.

Which of the following contribute(s) to the maintenance and/or activation of mucosal-associated invariant T (MAIT) cells?

	a)	MR1
	b)	commensal intestinal bacteria
	c)	H2-M3
	d)	TL
CorrectWrong: a and b are correct.Your answer has been saved.