8-3 NKT Cells

Work through the following questions, checking all the correct answers. For each question there may be more than one correct answer.

CD1d is recognized by which of the following surface molecules of NKT cells?

Which of the following statements are true?

	a)	The CD1d ligand that is responsible for thymic selection of NKT cells is thought to be a degradation product of membrane lipids.
	b)	Antigen receptors expressed by NKT cells express α chains comprising a unique combination of V and J segments.
	c)	Antigen receptors expressed by NKT cells express β chains comprising a unique combination of V and J and D segments.
	d)	NKT cells can express either CD4 or CD8.
	e)	NKT cells recognize glycosphingolipids and their degradation products bound to CD1d.
	f)	NKT cells, like canonical T cells, require priming to stimulate proliferation and differentiation of effector functions.
	g)	NKT cells participate in defense against Gram-negative bacteria.
	h)	Some NKT cell responses to infection depend upon degradation products of normal cell membranes.
CorrectWrong: a b d e g and h are trueYour answer has been saved.

α-Galactosylceramide (α-GalCer) is which of the following:

Immunity: Chapter 08, Specialized Lymphocytes in Early Responses and Homeostasis