Immunity: Chapter 06, B Cells and Humoral Immunity

Table of Contents

1. 6-1 Structure of Antibodies
2. 6-2 Structural Properties of Antibodies
3. 6-3 Effector Functions of Antibodies
4. 6-4 Monoclonal Antibodies
5. 6-5 Antibody-Based Methods: Radioimmunoassay and Hemagglutination
6. 6-6 Antibody-Based Methods: ELISA, Immunoblotting and FACS
7. 6-7 Antigen Receptors of B Lymphocytes
8. 6-8 B Cell Antigen Receptor Signaling and B Cell Coreceptors
9. 6-9 Early and T Cell-Independent Antibody Responses by B Cells
10. 6-10 Initiation of T Cell-Dependent Antibody Responses
11. 6-11 Hypermutation and Isotype Switching in the Germinal Center
12. 6-12 Selection and Differentiation of B Cells in the Germinal Center

6-2 Structural Properties of Antibodies

Work through the following questions, checking all the correct answers. For each question there may be more than one correct answer.

1

With regard to the different isotypes of antibodies: a) the class of antibody is determined by the heavy chain constant regions it contains. b) secretory IgA contains in addition to heavy and light chains, J chain and secretory components. c) IgG is the main form of antibody that protects mucosal surfaces. d) the largest antibody molecule is IgM. CorrectWrong: a, b and d are correct.Your answer has been saved.

2

Which of the following statements are true? a) The polymeric Ig receptor transports both polymeric IgA and monomeric IgA across epithelial cells to protect mucosal surfaces. b) FcRn is responsible for transporting a mother's IgG into her fetus. c) FcRn is responsible for the long half-life of IgG in the blood. d) A part of the polymeric Ig receptor remains attached to IgA that is secreted. CorrectWrong: b, c and d are true.Your answer has been saved.