Immunity: Chapter 05 Activation and Effector Actions of T Cells

Which of the following are thought to contribute to the maintenance of circulating naïve T cell numbers?

	a)	Stimulation through the TCR.
	b)	Thymocyte production from precursors in the bone marrow.
	c)	Proliferation of existing naïve T cells.
	d)	Inducible cytokines.
CorrectWrong: a, b and c are correct.Your answer has been saved.

Which of the following statements are true?

	a)	IL-7 is the most important cytokine for survival of naïve T cells.
	b)	IL-7 is induced in conditions of lymphopenia.
	c)	The antiapoptotic action of Bcl-2 is required for survival of naïve T cells.
	d)	Stimulation through the T cell receptor in the expansion phase of the T cell response leads to the induction of the proapoptotic regulator Bim
	e)	Positive costimulators promote survival of activated and effector T cells by inducing antiapoptotic regulators.
	f)	negative costimulator PD-L1 acts by inducing the proapoptotic regulator Bim.
CorrectWrong: a c d and e are trueYour answer has been saved.

Which of the following are thought to be particularly important in preventing the death of effector T cells in the periphery and/or B cell follicles?

	a)	B7
	b)	Bak
	c)	ICOSL
	d)	Bcl-XL
	e)	OX40L
CorrectWrong: c, d and e are correct.Your answer has been saved.