5-7 Clonal Expansion of Naïve T Cells in Secondary Lymphoid Tissue
Work through the following questions, checking all the correct answers. For each question there may be more than one correct answer.
1 |
Activation of T cells in lymph nodes induces changes in the surface molecules of the T cell that contribute to its retention in the lymph node and to its proliferation and differentiation at the surface of the activating dendritic cell. Which of the following molecules are induced on activation of T cells? |
2 |
Which of the following statements are true? |
3 |
Which of the following T cell surface molecules on binding ligand deliver(s) signals to the T cell that induce proliferation? |
4 |
Experimental deletion of which of the following molecules leads to uncontrolled proliferation of T lymphocytes and autoimmunity? |