Immunity: Chapter 05 Activation and Effector Actions of T Cells

Which of the following transcriptional regulators, all of which contribute to the activation of naïve T cells, is/are activated by Ca²⁺?

	a)	NF-κB
	b)	NFAT
	c)	AP-1
	d)	Oct1
CorrectWrong: b is correct.Your answer has been saved.

Which of the following statements are true?

	a)	Naïve T cells are induced to express the γ chain of the γc cytokine receptors on activation through the TCR.
	b)	Naïve T cells are induced to express the α chain of the IL-2 receptor on activation through the TCR.
	c)	Naïve T cells are induced to express IL-2 on activation through the TCR.
	d)	Signaling from CD28, which is activated by costimulators induced by infection, is generally required for T cell activation.
	e)	Signaling through CD28 activates Itk and PI3K.
	f)	Ca2+ signaling leads to DNA binding by Oct1.
	g)	Activation of the IL-2 gene requires convergence of signals from many pathways.
CorrectWrong: b, c, d, e and g are true.Your answer has been saved.

Which of the following signaling molecules is/are components of the pathway leading from TCR activation to the activation of MAP kinases?

	a)	calcineurin
	b)	Ras
	c)	Rac
	d)	protein kinase θ
CorrectWrong: b and c are correct.Your answer has been saved.