Immunity: Chapter 05 Activation and Effector Actions of T Cells

For which of the following interactions between T cells and dendritic cells do weak binding interactions as well as strong ones make a contribution to the sensitivity of the T cell response to antigen?

	a)	Interactions between MHC molecules and coreceptors.
	b)	Interactions between T cell receptors and peptide-MHC complexes.
	c)	Interactions between CD28 and B7.
CorrectWrong: b is correct.Your answer has been saved.

Which of the following statements are true?

	a)	The tyrosine kinase Lck is constitutively associated with the ζ chain of the T cell receptor.
	b)	ZAP-70 is a tyrosine kinase that is recruited to phosphorylated ITAMs in the cytoplasmic domains of T cell receptor chains.
	c)	The scaffold protein LAT is phosphorylated by the tyrosine kinase Itk.
	d)	Both Itk and the phospholipase PLC- γ1 are associated with the plasma membrane through binding to PIP3.
CorrectWrong: b and d are true.Your answer has been saved.

Which of the following molecules play(s) a part in cytoskeletal reorganization on TCR signaling?

	a)	Nck
	b)	Erk
	c)	Vav
	d)	Rac
	e)	DAG
CorrectWrong: a, c and d are correct.Your answer has been saved.