Immunity: Chapter 04, Adaptive Immunity and the Detection of Infection by T Lymphocytes

Table of Contents

1. 4-1 Dendritic Cells in the Induction of Adaptive Immunity
2. 4-2 The Structure and Function of MHC Molecules
3. 4-3 The MHC and Polymorphism of MHC Molecules
4. 4-4 Non-Classical MHC Class I Molecules
5. 4-5 Peptide Binding by MHC Molecules
6. 4-6 Antigen Presentation by Classical MHC Class I Molecules
7. 4-7 Antigen Presentation by MHC Class II Molecules
8. 4-8 Regulation of Antigen Presentation
9. 4-9 Specialized Features of Antigen Presentation by Dendritic Cells

4-3 The MHC and Polymorphism of MHC Molecules

Work through the following questions, checking all the correct answers. For each question there may be more than one correct answer.

1	Which of the following is/are applicable to classical MHC molecules? a) They display peptide antigen for recognition by T cells. b) They are highly polymorphic. c) They are scattered throughout the genome. d) They are polygenic. CorrectWrong: a, b and d are correct.Your answer has been saved.

2

Which of the following statements are true? a) All the genes contained in the major histocompatibility complex (MHC) encode proteins that play a part in antigen presentation. b) Every individual has hundreds of different genes for each MHC molecule. c) The variations, or polymorphisms, in MHC molecules are concentrated in the region forming the peptide-binding groove. d) All of the genes encoding the α and β chains of MHC molecules are polymorphic. e) Each different peptide-binding groove can bind a range of different peptides. CorrectWrong: c and e are true.Your answer has been saved.