Immunity: Chapter 04, Adaptive Immunity and the Detection of Infection by T Lymphocytes

Table of Contents

1. 4-1 Dendritic Cells in the Induction of Adaptive Immunity
2. 4-2 The Structure and Function of MHC Molecules
3. 4-3 The MHC and Polymorphism of MHC Molecules
4. 4-4 Non-Classical MHC Class I Molecules
5. 4-5 Peptide Binding by MHC Molecules
6. 4-6 Antigen Presentation by Classical MHC Class I Molecules
7. 4-7 Antigen Presentation by MHC Class II Molecules
8. 4-8 Regulation of Antigen Presentation
9. 4-9 Specialized Features of Antigen Presentation by Dendritic Cells

4-1 Dendritic Cells in the Induction of Adaptive Immunity

Work through the following questions, checking all the correct answers. For each question there may be more than one correct answer.

1	Immature dendritic cells are characterized by: a) many receptors for cellular debris and microbial components. b) high levels of surface MHC molecules. c) vigorous phagocytic activity. d) receptors for inflammatory chemokines. CorrectWrong: a, c and d are correct.Your answer has been saved.

2

Which of the following statements are true? a) Maturation of immature dendritic cells depends on stimulation by infection. b) On maturation, dendritic cells migrate to secondary lymphoid tissues. c) An essential property of mature activated dendritic cells is the expression of high levels of the costimulatory molecules B7-1 and B7-2. d) The TLRs of dendritic cells are the most important for internalization of infectious particles. CorrectWrong: b and c are true.Your answer has been saved.

3	Which of the following induce differentiation of dendritic cells to a mature activated state? a) IL-1. b) TLRs. c) CD28. d) TNF. CorrectWrong: a, b and d are correct.Your answer has been saved.