Immunity: Chapter 03, Innate Immunity

Type 1 interferons induce several proteins that block viral replication and viruses in turn produce several proteins that block the antiviral actions of interferons. A particularly common target for blocking by antiviral proteins is:

	a)	PKR.
	b)	STAT1.
	c)	2',5'-oligo A synthetase.
	d)	Mx.
CorrectWrong: a is correct.Your answer has been saved.

Which of the following statements are true?

	a)	Oligo A synthetases induced by type 1 interferons act specifically on viral DNA and protein synthesis.
	b)	Type 1 interferons are produced only by cells of the immune system.
	c)	Chronic hepatitis virus infection can be treated with interferon.
	d)	Some viruses evade the antiviral actions of interferons by blocking phosphorylation of IRF-3 and IRF-7.
CorrectWrong: c and d are true.Your answer has been saved.

Double-stranded RNA (dsRNA) binds and activates:

	a)	eIF2α.
	b)	2',5'-oligo A synthetase.
	c)	PKR.
	d)	influenza virus NS1.
CorrectWrong: b and c are correct.Your answer has been saved.