Immunity, Chapter 02, Signaling and Adhesive Molecules of the Immune System

Which of the following are properties of γc interleukin receptors?

	a)	One chain that is common to all of the receptors, with a second that is specific for different interleukins.
	b)	Signalling through Jak3.
	c)	Ligands that are composed of one four-helix-bundle cytokine and one cytokine-receptor-like chain.
	d)	A unique chain that recruits specific STATs and thus determines the cellular response.
CorrectWrong: a, b and d are correct.Your answer has been saved.

Two of the γc interleukin receptors have three chains rather than two, the third chain conferring high-affinity binding to the interleukin: which, if any, of the following interleukins is/are the one(s) that bind(s) to these receptors?

	a)	IL-2.
	b)	IL-4.
	c)	IL-7
	d)	IL-15.
CorrectWrong: a and d are correct.Your answer has been saved.

Which of the following statements are true?

IL-6-related receptors:

	a)	have a common signaling chain.
	b)	signal through chains that bind four-helix-bundle interleukins with a second, non-signalling chain that may be part of the receptor or part of the ligand.
	c)	include IL-12 and IL-23 receptors as well as the IL-6 receptor.
	d)	signal through Jak3.
CorrectWrong: b and c are true.Your answer has been saved.