Immunity, Chapter 02, Signaling and Adhesive Molecules of the Immune System

Table of Contents

1. 2-1 The Immunoglobulin Superfamily: Structural Features
2. 2-2 Signaling by Immunoglobulin Superfamily Receptors
3. 2-3 Adhesion Molecules of the Immunoglobulin Superfamily
4. 2-4 Integrins in Immune Function
5. 2-5 C-Type Lectins and Carbohydrate Recognition
6. 2-6 Cytokines and Cytokine Receptors
7. 2-7 Cytokine Receptors that Signal via the Jak-STAT Pathway
8. 2-8 Shared Subunits in Subfamilies of Type I Cytokine Receptors
9. 2-9 The TNF Superfamily of Cell Regulators
10. 2-10 NF-κB and Inflammatory Cytokine Action
11. 2-11 Molecular Control of Apoptosis
12. 2-12 Regulation of Apoptosis by Bcl-2 Family Members
13. 2-13 Chemokines and Chemokine Receptors
14. 2-14 Chemokines, Integrins and Selectins and Immune-Cell Homing

2-3 Adhesion Molecules of the Immunoglobulin Superfamily

Work through the following questions, checking all the correct answers. For each question there may be more than one correct answer.

1	Which of the following statements are true? Adhesive molecules of the immunoglobulin superfamily: a) contribute to T cell activation. b) fall into two groups. c) include the integrins. Correct.Wrong: b and c are true.Your answer has been saved.

2

Which of the following statements are true? Members of the CD2 family of adhesive molecules: a) engage in homophilic interactions. b) interact with integrins. c) engage in interactions that depend mainly on charge complementarity rather than shape complementarity and are therefore easily made and lost. d) participate in recruitment of immune cells to different sites in the body. Correct.Wrong: a and c are true.Your answer has been saved.