Immunity: Chapter 01, Overview of the Immune Response

Table of Contents

1. 1-1 Cells of the Immune System: Differentiation in the Bone Marrow
2. 1-2 Cells of the Immune System: Functional Characteristics
3. 1-3 Macrophage and Dendritic Cell Subsets
4. 1-4 Clonal Selection of Antigen-Specific Lymphocytes
5. 1-5 Major Histocompatibility Molecules and the Detection of Infection
6. 1-6 The Lymphoid System and Lymphocyte Circulation
7. 1-7 Architecture of Secondary Lymphoid Tissues
8. 1-8 The Course of an Immune Response

1-4 Clonal Selection of Antigen-Specific Lymphocytes

Work through the following questions, checking all the correct answers. For each question there may be more than one correct answer.

1

The antigen receptors of lymphocytes have: a) two distinct types of chains, one forming the relatively invariant parts called constant regions and the other forming the variable regions containing the antigen-binding sites. b) variable antigen-binding sites encoded by genes assembled from different combinations of gene segments. c) two distinct types of chains, each containing both variable and constant regions. CorrectWrong: b and c are correct.Your answer has been saved.

2

Which of the following statements are true? a) Clonal selection can ensure that each lymphocyte in an individual has receptors all bearing the same antigen-binding site. b) Clonal selection is the basis for the production of large numbers of antigen-specific lymphocytes in an adaptive immune response to foreign antigen. c) Clonal selection acts on populations of lymphocytes each bearing receptors all of which have the same antigen-binding site. Correct.Wrong: b and c are true.Your answer has been saved.