Chapter 21

Instructions

Choose your answers from a-d by clicking the radio button next to each choice and then press 'Submit' to get your score.

Which of the following is correct regarding systemic lupus erythematosus?

a) The underlying pathogenesis appears to be deposition of circulating immune complexes in multiple tissues and organs.

b) Most patients have circulating anti-neutrophil cytoplasmic antibodies (ANCA).

c) The disease usually comes to light following investigation of renal impairment.

d) The disease is a common cause of systemic amyloidosis.

Which of the following is correct regarding systemic sclerosis?

a) Raynaud's disease is a common early manifestation.

b) Both pulmonary and systemic hypertension are recognized complications.

c) Acute renal failure due to glomerulosclerosis is a life threatening complication.

Which of the following is correct regarding sarcoidosis?

a) Is often picked up incidentally on a chest radiograph.

b) Is now known to have an infectious aetiology.

c) Is characterized histologically by the presence of caseating granulomas in involved tissues.

d) Is a common cause of hypocalcaemia.

Which of the following is correct regarding amyloidosis?

a) Cell death is due to accumulation of intracellular amyloid.

b) Localized amyloid deposition may be seen in the pancreas of type 1 diabetics.

c) Renal amyloidosis is due to deposition of amyloid in the renal tubule system.

d) Rheumatoid arthritis is a common cause in the UK.

Which of the following is correct regarding vasculitis?

a) A negative temporal artery biopsy excludes giant cell arteritis.

b) ANCA positivity is a helpful diagnostic feature of polyarteritis nodosa.

c) Small vessel vasculitides may present with acute renal failure.

d) Granulomatous inflammation is a feature of microscopic polyarteritis.