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Question 1

Which of the following is correct regarding benign skin neoplasms?

a) Seborrhoeic keratoses are benign neoplasms composed of melanocytes.

b) Melanocytic nevi may be junctional, compound, or intraepidermal.

c) Dermatofibroma is a benign soft tissue neoplasm of the skin which commonly occurs on the lower leg of young women.

d) Pyogenic granuloma is a benign neoplasm in which neutrophils and granulomas are prominent.

Question 2

Which of the following is correct regarding dysplastic nevi?

a) They are melanocytic lesions that show both clinical and histological atypia.

b) They are uncommon lesions.

c) All patients with a dysplastic nevus require regular follow up by a dermatologist.

d) Most develop into a malignant melanoma if not excised.

Question 3

Which of the following is correct regarding basal cell carcinomas?

a) They are the second most common cutaneous malignancy.

b) They are most commonly seen on sun exposed sites of the elderly.

c) Histologically, they consist of neoplastic keratinocytes showing keratin formation.

d) Complete surgical excision is the treatment of choice, so as to prevent metastases.

Question 4

Which of the following is correct regarding squamous cell carcinoma of the skin?

a) Most are unrelated to sun exposure.

b) Most arise from actinic keratoses.

c) They have a high risk of lymph node metastases.

d) Cryotherapy is the treatment of choice.

Question 5

Which of the following is correct regarding malignant melanoma of the skin?

a) The incidence in the UK is now falling.

b) In situ melanomas may be classified as being in either radial or vertical growth phases.

c) The Breslow thickness is measured from the granular layer of the epidermis to the deepest point of invasion of the tumour.

d) The Clark level is the most important prognostic indicator.

Question 6

Which of the following is correct regarding atopic dermatitis?

a) Some 20% of children are affected.

b) It is due to a delayed type hypersensitivity reaction to environmental antigens in the skin.

c) It typically affects the flexor surfaces of the knees and elbows of infants, and the face and trunk of older children.

d) Exacerbations may occur due to secondary infection by S. aureus or herpes simplex virus.

Question 7

Which of the following is correct regarding psoriasis?

a) The typical lesion is a well demarcated erythematous macule with a silvery scale.

b) Guttate psoriasis is the commonest pattern.

c) The lesions are thought to develop from keratinocyte hyperproliferation driven by activated T lymphocytes.

d) About half of all patients develop psoriatic arthropathy.

Question 8

Which of the following is correct regarding acne?

a) Poor diet is relevant in the pathogenesis.

b) Obstruction to sweat glands is the underlying problem.

c) Comedones are the result of inflammation caused by overgrowth of the bacterium P. acnes.

d) Treatment with steroids may cause acne.

Question 9

Which of the following is correct regarding blistering disorders of the skin?

a) Blisters are caused by separation of keratinocytes from one another.

b) Pemphigus is caused by autoantibodies to components of the dermoepidermal junction.

c) Pemphigoid causes numerous delicate blisters which rupture easily.

d) Dermatitis herpetiformis shows a strong association with underlying Crohn's disease.

Question 10

Which of the following is correct regarding skin infections?

a) Impetigo is a highly infectious skin infection caused by S. epidermidis.

b) Benzylpenicillin and flucloxacillin are appropriate treatments for cellulitis.

c) Tinea corporis refers to scalp dermatophytosis.

d) Molluscum contagiosum is caused by a human papillomavirus.

Oxford University Press, Online Resource Centre, Chapter 16.

Chapter 16

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