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Question 01

Risk factors for prostate cancer include which one of the following?

a) Castration before age 40 years

b) Black race

c) Asian race

d) Young age

Question 02

Which of the following is true regarding prostate cancer?

a) The lifetime risk of developing it is 10%

b) It is the most common cause of cancer death in men

c) Incidence is falling

d) It accounts for approximately 30% of all cancers in men

Question 03

In diagnosis of prostate cancer:

a) all patients should have a digital rectal examination (DRE)

b) most patients with a PSA>4ng/ml will have prostate cancer

c) urinary obstructive symptoms are highly suggestive

d) biopsy is usually by fine needle aspiration (FNA)

Question 04

Which one of the following statements is true of prostate cancer?

a) Gleason score 3 describes a poorly differentiated tumour

b) 65% of patients with Gleason score 5-7 will die from prostate cancer within 15 years

c) PSA >50ng/ml is often associated with distant bone metastases

d) T2 describes a tumour that has extended through the capsule

Question 05

Which of the following statements is true in management of prostate cancer which is confined to the prostate gland?

a) Active surveillance is a valid approach

b) Prostatectomy has been shown to be superior to radiotherapy

c) Radiotherapy causes impotence in 50% of patients

d) Prostatectomy leads to long term incontinence in 5% of patients

Question 06

In metastatic prostate cancer:

a) median survival is 18 months

b) hormone therapy will produce responses in around 70% of men with bone metastases

c) the median response duration of hormone therapy is 8 months

d) chemotherapy is the most commonly used systemic treatment used

Question 07

Side effects of hormone treatment rarely include which one of the following?

a) Hot flushes

b) Loss of libido and potency

c) Osteoporosis

d) Myelopsuppression

Question 08

In treatment of hormone refractory prostate cancer:

a) docetaxel and prednisolone have been shown to increase median survival by 2 months

b) mitoxantrone and prednisolone have been shown to increase median survival by 1 month

c) withdrawing anti-androgen therapy confers no benefit

d) intravenous radio-isotope therapy has been shown to increase median survival by 3 months

Question 09

Which one of the following statements is true of prostate bone metastases and their complications?

a) Most fractures occur as the result of trauma

b) Spinal cord compression is usually managed surgically

c) Prophylactic orthopaedic intervention may be required for bone lesions at high risk of fracture

d) Bisphosphonates may help to reduce bone pain but do not reduce the number of cancer-associated skeletal events

Question 10

Which one of the following symptoms is rare in patients with progressive prostate cancer?

a) Symptomatic anaemia

b) Urinary retention

c) Sexual dysfunction

d) Haematemesis

Oxford University Press, Online Resource Centre, Prostate Cancer.

Prostate Cancer

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