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Question 01

Which of the following is true of ovarian cancer?

a) It is the most common gynaecological cancer in the UK

b) It is the second commonest cancer in females

c) Approximately 10% are familial

d) Median age of diagnosis is 53 years

Question 02

Risk factors for ovarian cancer include which of the following?

a) Young age

b) Nulliparity

c) Multiple pregnancies

d) Prolonged use of oral contraceptive pill

Question 03

Which one of the following statements regarding screening for ovarian cancer is correct?

a) Screening using CA-125 is offered to all women between the ages of 50 and 75 years in the UK

b) Studies have shown an approximate 40% reduction in mortality with screening

c) Serum CA-125 has a sensitivity of 50% and a specificity of 20%

d) Trials of potential screening methods for ovarian cancer are ongoing

Question 04

Which one of the following symptoms is an uncommon presentation of ovarian cancer?

a) Abdominal pain

b) Chest pain

c) Weight loss

d) Abdominal distension

Question 05

Which of the following is true of staging of ovarian cancer?

a) Stage III describes disease which has spread to the peritoneum beyond the pelvis

b) Stage I tumours are common

c) Any pleural effusion equals stage IV disease

d) <70% of patients present with disease which has spread beyond the pelvis

Question 06

Which of the following statements is true regarding prognosis of ovarian cancer?

a) Stage I disease has a median 5 year survival of <70%

b) Stage II disease has a median 5 year survival of 60%

c) Stage III disease has a median 5 year survival of 20%

d) Stage IV disease has a median 5 year survival of 10%

Question 07

In treatment of ovarian cancer:

a) Germ cell ovarian tumours require total abdominal hysterectomy (TAH), bilateral salpingo-oopherectomy (BSO), omentectomy and lymph node biopsies

b) Chemotherapy is the most important modality in the treatment of epithelial ovarian cancer

c) Optimal debulking describes surgery where no tumour remains which measures >2cm

d) Optimal debulking surgery has been demonstrated to significantly improve survival

Question 08

Which of the following statements is true of first line chemotherapy for epithelial ovarian cancer?

a) Following platinum/taxane chemotherapy 5 year survival is >40%

b) Response rates to platinum/taxane chemotherapy are approximately 50%

c) Median survival following platinum/taxane chemotherapy is 2-3 years

d) The most commonly used chemotherapy is a combination of docetaxel and oxaliplatin

Question 09

Which of the following is true of treatment for relapsed epithelial ovarian cancer?

a) Platinum chemotherapy is the optimum therapy for patients who relapse less than 6 months after completion of platinum based chemotherapy

b) The response rate to platinum chemotherapy is approximately 60% in those who relapse more than 2 years after completion of platinum based first line chemotherapy

c) Most patients can be cured with further chemotherapy

d) Most patients can be cured with further surgery

Question 10

In metastatic epithelial ovarian cancer:

a) ascities usually responds well to diuretics

b) bowel obstruction is common and is usually managed medically using subcutaneous medication given via a syringe driver

c) opioid analgesics should be avoided

d) lymphoedema is rare and treatment of it is generally ineffective

Oxford University Press, Online Resource Centre, Ovarian Cancer.

Ovarian Cancer

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