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Question 01

Which of the following are true of breast cancer?

a) The life time risk for a woman of developing breast cancer is 1/9.

b) For most women a specific cause of their breast cancer is known.

c) Prognosis is worse for affluent women.

d) Incidence of breast cancer is decreasing.

Question 02

Risk factors for breast cancer include?

a) Young age

b) Young age at menopause

c) Young age at first birth

d) Young age at menarche

Question 03

The following statements regarding screening for breast cancer are correct?

a) Mammography is offered to all women between the ages of 50 and 75 years in the UK.

b) Studies have shown an approximate 30% reduction in mortality with screening using mammography.

c) Most radiographically suspicious lesions are subsequently confirmed as malignant.

d) Mammography is less sensitive in postmenopausal women.

Question 04

Which of the following is not necessary when a patient first presents with a breast lump?

a) Fine needle aspiration (FNA)

b) Chest x-ray

c) Examination of axillary lymph nodes

d) Examination of breasts with patient supine

Question 05

Which of the following are good prognostic factors in breast cancer?

a) Oestrogen receptor positivity

b) Grade III tumour

c) HER 2 receptor overexpression

d) Lymph node involvement

Question 06

Which of the following statements is true regarding adjuvant treatment for early breast cancer?

a) Radiotherapy is indicated after breast conserving surgery only if >4 nodes positive or tumour close to the resection margin.

b) Aromatase inhibitors are replacing tamoxifen in premenopausal women due to better outcomes and greater tolerability.

c) Combination chemotherapy reduces recurrence and improves survival in selected patient groups.

d) No survival benefit has been demonstrated with use of trastuzumab (herceptin) in the adjuvant setting.

Question 07

In treatment of metastatic breast cancer…

a) …chemotherapy is superior to endocrine therapy.

b) …bisphosphonates are used to control hypocalcaemia.

c) …responses to endocrine therapy tend to occur within 2 months of starting treatment.

d) …trastuzumab (herceptin) in combination with chemotherapy improves survival in patients who have tumours that overexpress HER 2.

Question 08

Which of the following statements is true of breast cancer treatment?

a) Mastectomy is superior to breast conservation surgery.

b) Chemotherapy can be used safely in the first trimester of pregnancy.

c) Radiotherapy should be given to all male breast cancer patients after mastectomy.

d) Paget's disease of the nipple should be treated with wide local excision.

Question 09

Which of the following is a rare site of breast cancer metastases?

a) Brain

b) Kidney

c) Liver

d) Bone

Question 10

Which of the following statements is true of palliative treatment of metastatic breast cancer?

a) Hypercalcaemia should be treated with increased oral fluids and oral bisphosphonates.

b) Increased back pain and 'weak legs' requires prompt investigation.

c) Bisphosphonates are used in treatment of liver metastases.

d) Neuropathic pain usually responds quickly to opioid analgesics.

Oxford University Press, Online Resource Centre, Breast Cancer.

Breast Cancer

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