Chapter 10

Instructions

Choose your answers from a-d by clicking the radio button next to each choice and then press 'Submit' to get your score.

Question 1

Complete the following sentence. The Philadelphia chromosome:

a) is an example of gene amplification.

b) is a product of a reciprocal translocation.

c) causes Burkitt's lymphoma.

d) causes retinoblastoma.

Question 2

Which of the following is not a tumour suppressor gene?

a) APC

b) NF1

c) RB1

d) RET

Question 3

Which of the following is not a familial cancer syndrome

a) Familial adenomatous polyposis

b) Li-Fraumeni syndrome

c) Von Hippel-Lindau syndrome

d) Waardenburg syndrome

Question 4

Marked microsatellite instability is a feature of:

a) familial adenomatous polyposis.

b) hereditary non-polyposis colon cancer (HNPCC).

c) multiple endocrine adenomatosis type 2.

d) neurofibromatosis 1.

Question 5

Male breast cancer is associated with mutations in ___.

a) BRCA1

b) BRCA2

c) NF1

d) RET

Oxford University Press, Online Resource Centre, Chapter 10.

Chapter 10

Instructions

Question 1

Question 2

Question 3

Question 4

Question 5