Chapter 08

Instructions

Choose your answers from a-d by clicking the radio button next to each choice and then press 'Submit' to get your score.

Normal adult haemoglobin (Hb A) consists of:

a) two α (alpha) and two β (beta) chains.

b) two α and two γ (gamma) chains.

c) two α and two δ (delta) chains.

d) four γ chains.

Question 2

Severe anaemia at birth is a feature of what?

a) Alpha-thalassaemia

b) Beta-thalassaemia

c) Hereditary persistence of fetal haemoglobin

d) Sickle cell disease

Question 3

The mutation in sickle-cell disease consists of:

a) a deletion.

b) a duplication.

c) an insertion.

d) a point mutation.

Question 4

The common mutation in α-thalassaemia consists of:

a) a deletion.

b) a duplication.

c) an insertion.

d) a point mutation.

Question 5

The mutational mechanism in δβ-thalassaemia consists of:

a) a deletion.

b) a duplication.

c) an insertion.

d) a point mutation.