Chapter 07

Instructions

Choose your answers from a-d by clicking the radio button next to each choice and then press 'Submit' to get your score.

Question 1

If an autosomal recessive disorder which shows Hardy-Weinberg equilibrium has an incidence of 1 in 6400 then the frequency of carriers is approximately _______.

a) 1 in 20

b) 1 in 40

c) 1 in 80

d) 1 in 160

Question 2

If an X-linked recessive disorder is in Hardy-Weinberg equilibrium and the incidence in males equals 1 in 100, then the expected incidence of affected homozygous females would be _______.

a) 1 in 1000

b) 1 in 4000

c) 1 in 10 000

d) 1 in 40 000

Question 3

Repeat core sequences consisting of 2, 3, or 4 base pairs are known as what?

a) Single nucleotide polymorphisms (SNPs)

b) Microsatellites

c) Minisatellites

d) Satellites

Question 4

With which of the following relatives is an individual most likely to share a common HLA haplotype?

a) Father

b) Mother

c) Sister

d) Son

Question 5

Which of the following disorders is not suitable for population carrier screening?

a) Cystic fibrosis

b) Oculocutaneous albinism

c) Sickle cell disease

d) Tay-Sachs disease

Oxford University Press, Online Resource Centre, Chapter 07.

Chapter 07

Instructions

Question 1

Question 2

Question 3

Question 4

Question 5