Chapter 06

Instructions

Choose your answers from a-d by clicking the radio button next to each choice and then press 'Submit' to get your score.

Question 1

The proportion of genes shared by first cousins is on average ___.

a) 1/2

b) 1/4

c) 1/8

d) 1/16

Question 2

Which of the following genes conveys susceptibility for polygenic Alzheimer disease?

a) APP

b) PS1

c) PS2

d) APOE

Question 3

Which of the following statements about Hirschsprung disease is incorrect?

a) It shows an association with Down syndrome.

b) It is more common in girls than in boys.

c) RET is a major susceptibility gene.

d) Recurrence risks are greater for long segment disease than for short segment disease.

Question 4

Which of the following conditions does not show multifactorial inheritance?

a) Pyloric stenosis

b) Schizophrenia

c) Spina bifida (neural tube defects)

d) Marfan syndrome

Question 5

In a condition such as schizophrenia the recurrence risk will be greatest for which of the following relatives of an affected individual?

a) Brother

b) Nephew

c) Grandchild

d) Aunt

Oxford University Press, Online Resource Centre, Chapter 06.

Chapter 06

Instructions

Question 1

Question 2

Question 3

Question 4

Question 5