Chapter 04

Instructions

Choose your answers from a-d by clicking the radio button next to each choice and then press 'Submit' to get your score.

Male to male transmission is a key feature of which pattern of inheritance?

a) Autosomal dominant

b) Autosomal recessive

c) X-linked dominant

d) X-linked recessive

Question 2

Consanguinity shows a strong association with which pattern of inheritance?

a) Autosomal dominant

b) Autosomal recessive

c) X-linked dominant

d) X-linked recessive

Question 3

Which of the following disorders does not show X-linked inheritance?

a) Duchenne muscular dystrophy

b) Tay-Sachs disease

c) Haemophilia A

d) Haemophilia B

Question 4

Which of the following would result in Angelman syndrome?

a) Maternal UPD 15

b) Paternal UPD 15

c) Deletion in the paternally derived chromosome 15

d) A mutation in the SNRPN promoter

Question 5

Leber's hereditary optic atrophy is caused by a mutation in:

a) chromosome 12.

b) chromosome 18.

c) chromosome 21.

d) mitochondrial DNA.